Kakeru, a former elite runner at high school, is chased for stealing food. He is saved by Kansei University student Haiji, who is also a runner. Haiji persuades Kakeru to live in the old apartment "Chikuseisou" where he plans to team up with fellow residents to enter Hakone Ekiden Marathon, one of the most prominent university races in Japan. Kakeru soon finds out that all of the residents except for Haiji and himself are complete novices.

Jinta Yadomi and his group of childhood friends have become estranged after a tragic accident split them apart. Now in their high school years, a sudden surprise forces each of them to confront their guilt over what happened that day and come to terms with the ghosts of their past.

After losing her mother and her homeland, Sitara’s despair transforms into determination with the power of knowledge. New possibilities unfold when a family of scholars takes her in, deepening her education. Meanwhile, Genghis Khan’s Mongol Empire conquers nation after nation, nearing Sitara’s new home. After the Fourth Prince of the empire takes her captive, a flame of revenge is ignited.

As the world is threatened by the sudden appearance of a mysterious alien mothership, best friends Koyama Kadode and Nakagawa “Ontan” Oran carry on about their high school life. But as they grow up, they face existential questions, learning adulthood’s complexities and that the true threat may not be from above.