Brandon, a thirty-something man living in New York, eludes intimacy with women but feeds his deepest desires with a compulsive addiction to sex. When his younger sister temporarily moves into his apartment, stirring up bitter memories of their shared painful past, Brandon's life, like his fragile mind, gets out of control.

Seduced by the challenge of an impossible case, the driven Dr. Carl Jung takes the unbalanced yet beautiful Sabina Spielrein as his patient. Jung’s weapon is the method of his master, the renowned Sigmund Freud. Both men fall under Sabina’s spell.